Co-codamol

Co-codamol tablets are a combination of codeine phosphate and paracetamol, also known as acetaminophen. The first medication, codeine phosphate is an opiate, also known as an opioid, which the body changes into morphine while it is metabolised. It is derived from the sap of the opium poppy and was first founded by Pierre Jean Robiquet in 1832.

It is commonly known as the most popular opiate in the world and is one of the most used medications in the world. It is available via prescription or over-the-counter as part of a cough syrup mixture. The second medication contained in Co-codamol tablets is paracetamol. This medication is used to treat a variety of mild to moderate painful conditions, such as general aches and pains, migraines, and fevers.

There is debate amongst the scientific community whether this medication was discovered in 1852 by a scientist called Charles Gerhardt or by Harmon Northrop Morse at Johns Hopkins University in 1877. In most countries, it first became available in 1956 as Panadol, available only by prescription, and was promoted as a safer alternative to aspirin, as children could take it.

Since then, it became easily available over the counter and is now considered the most used medication for pain and fever.

What is Co-codamol Used for?

When people look to find Co-codamol online, it is usually for the treatment of pain, although it can be used to bring down fevers or to treat the symptoms of cold and flu. Pain can be described in several ways. Cambridge Dictionary describes it as ‘a feeling of physical suffering caused by injury or illness'.

Merriam-Webster Dictionary goes into further detail and describes it as 'a localized or generalized unpleasant bodily sensation or complex of sensations that cause mild to severe physical discomfort and emotional distress and typically results from bodily disorder (such as injury or disease)'.

Regardless of how you would describe pain, we have all experienced it to some extent or another. When the pain becomes too much to bear, or starts to interfere with your daily activities, work performance or social life, then people tend to buy painkillers . Painkillers are useful because they can help to treat this kind of debilitating pain instantly so that the sufferer's normal life can resume.

One 2016 study that was conducted found that 20.4% of US adults suffer from chronic pain, and 8.0% of US adults suffer from high-impact chronic pain. Chronic pain is also known as long-term pain and is the type of pain that is most likely to be treated with painkillers. This type of pain does not have to be constant; it can be on or off but must be present for over three months. This type of pain is usually caused by a medical condition.

The other type of pain is called acute pain, or short-term pain. This type of pain is where the pain is present for less than three months. This is usually related to an injury or short-term illness so when the injury is healed, or the short-term illness is cured, so is the pain. In relation to the conditions that this medication is used for, they are a variety of chronic pain conditions and acute pain.

Some of the more common ones are as follows:

• Headaches and Migraines : The frequency of these can vary depending on the person, some people can suffer from one every year or so, whereas in certain unfortunate cases, the sufferer can have migraine attacks for at least 8 days a month. This would then be categorized as chronic migraines.
• Muscular pain: usually a result of injuries, which can be sustained from normal activities in everyday life, moderate to severe injuries sustained during physical activities such as sports, or more significant injuries sustained from accidents.
• Toothache: this can either be prescribed if someone is suffering from dental abscesses, or because of pain derived from dental surgery.

How Co-codamol Works

As Co-codamol is a combination of two different painkillers, paracetamol, and codeine phosphate, it works to attack pain in two different ways. The first medication, paracetamol, works by reducing the production of prostaglandins in the central nervous system, which consists of the brain and spinal cord. Prostaglandins are a group of lipids made at sites of tissue damage or infection.

They control inflammation, blood flow and the formation of blood clots, but more importantly, they also increase nerve sensitivity. The reason they perform this function is so that when we suffer from an injury, the pain that results ensures that we do not suffer from further damage. By inhibiting the production of prostaglandins, paracetamol ensures that the amount of pain that our brain tells us we are feeling is reduced.

The other medication, codeine phosphate, works in a similar way to other opioids, by binding to receptors in the central nervous system that work by blocking pain. This works in the same way as endorphins that are produced in the body. These receptors, located on nerve endings, regulate messages sent to the brain, which increases our pain threshold.

How Long Co-codamol Lasts

The effects of this medication generally last between four to six hours, although this depends on the Co-codamol dosage that is taken. If a higher dosage is taken, this will likely increase the amount of time that the effects last, in addition to increasing the analgesic effects of the tablets. This medication starts to work after around 30 minutes, with the peak concentration of the medication being reached after around 60 minutes.

The paracetamol contained in the medication is well-absorbed in the intestinal tract after leaving the stomach. It is subsequently metabolised in the liver. The half-life of paracetamol is between 1-3 hours, which means that this is how long it takes for the concentration of medication in the body to be halved.

In relation to codeine; this is absorbed through the gastrointestinal tract. Peak concentrations of this medication are reached about one hour after consumption. The medication is subsequently excreted exclusively through the kidney. The elimination half-life of codeine is reported to be between 3 and 4 hours.

There are different factors that can affect how quickly this medication is processed in the body. Some of these are:

• Metabolism: if you have a quick metabolism, you will process medication faster than people with slower metabolisms.
• Weight: people who weigh more than the average man or woman will process medications more slowly than others who weigh less than the average person.
• Age: as people get older, they tend to process medications more slowly, partly to do with reduced organ and metabolic function.
• Liver and Kidney Health: this medication is comprised of paracetamol and codeine. Because paracetamol is processed via the liver, and codeine is processed via the kidneys, the function of these two organs can affect how quickly Co-codamol tablets are processed.

Co-codamol Dosage for Pain Relief

If you are looking for advice on which Co-Codamol dosage you should take, then we have some information contained in this section. Firstly, there are several Co-codamol strengths available. The dosages are split between the amount of codeine in the medication and the paracetamol in the medication, with the first number being the amount of codeine, and the second number the amount of paracetamol. The amount of paracetamol stays the same in all formulations, 500 mg, but the amount of Codeine changes for each dosage.

• Co-codamol 8/500 mg is the weakest dose, and this is available as Co-codamol over the counter in pharmacies, with no prescription needed.
• Co-codamol 30/500 mg is the strongest dose, and the amount that is recommended for moderate or chronic pain. This is only available via prescription or an online pharmacy.
• If you feel that Co-codamol 30/500 mg is too strong for your purposes, or you want to reduce the already low risk of side effects further, you can split the tablet and take Co-codamol 15/500 mg instead.

For chronic pain, no more than one Co-codamol 30/500 mg tablet should be taken every 4-6 hours, and no more than four tablets should be taken per day. It is important that you never take more than the recommended Co-codamol dosage and that you do not take this medication for longer than three days in a row. If you need to, you should seek advice from your doctor. This medication can be taken with or without food, but your choice should remain consistent while taking it, to ensure that you are absorbing the same amount of medication.

Co-codamol Side Effects

Before you buy Co-codamol online, you should first conduct research into the potential Co-codamol side effects that can occur when taking this medication. The following list is not exhaustive, but is some of the more common side effects that can occur:

• Constipation
• Nausea
• Sleepiness

It is important that you do not consume Co-codamol and alcohol together, as this can increase the risk of side effects. Some people may experience an allergic reaction to certain medications. If you do experience an allergic reaction after you buy Co-codamol 30 500 online, you should immediately seek emergency medical attention.

Is Co-codamol Safe for Everyone?

This medication has been fully approved for medical use in most countries by various international regulatory bodies. However, whenever you get painkillers , there is always a risk associated with taking them, and obtaining Co-codamol online is no different. It is important to regulate the Co-codamol strengths that you take, so that there is no risk of taking too much.

There is a history of the potential for opioid dependence, and by extension, Co-codamol overdose, if more than the recommended dose is taken, or if this medication is taken alongside other medications that may increase the effects such as medications containing other opioids or paracetamol. If you have taken the maximum dose of this medication and are still experiencing pain, you can take Co-codamol and ibuprofen together, for increased pain reduction.

Co-codamol vs Codeine

Co-codamol is known as a compound analgesic, which means it is a combination of two different painkillers, brought together into one tablet to enhance the painkilling effects of both. These types of compound analgesics are also preferred as it reduces the number of tablets that need to be taken per day. Because it contains not only codeine, but also paracetamol, it works in several different ways to attack pain at the source. It is a more powerful painkiller than codeine alone, due to the addition of paracetamol.

Before You Buy Co-codamol Online

Before taking this medication, you should speak with your doctor, who will be able to advise whether it interferes with any existing medication that you are taking. Additionally, they can inform you whether it is safe for you to take this medication if you are suffering from any medical conditions.

You should take a lower dose of this medication if you suffer from any of the following conditions, although this is not a full list:

• Chronic lung disease
• Kidney disease
• Liver disease

Additionally, before taking any medication, you should always attempt other methods of dealing with pain first. One method that anecdotal evidence suggests can be effective is physical therapy. Not only can this reduce the current pain that you are feeling, but it can also prevent the possibility of future injuries.

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